Optical Coherence Tomography Retinal Nerve Fibre Layer and Ganglion Cell Complex Measurements in Normal Southern Nigerian Eyes

AI Generated Summary*

Retrospective cross-sectional analysis of spectral-domain OCT records from 304 eyes of 152 healthy adults at a southern Nigerian teaching hospital yielded reference values for retinal nerve fibre layer (RNFL), ganglion cell layer (GCL), and GCL plus inner plexiform layer thickness. Participants were half female and aged 18 to 71. Mean RNFL measured 111.49 (right) and 111.96 (left); GCL averaged about 66 and GCL+IPL about 104. Nearly all parameters declined with age, sex had minimal influence, between-eye variability was small, and inferior sectors exceeded superior ones. Against the device's normative database, RNFL emerged significantly thicker, whereas GCL and GCL+IPL were thinner (p < 0.001). The authors argue these disparities deserve consideration when using OCT for glaucoma in Nigeria.

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