Optical coherence tomography in multiple sclerosis

AI Generated Summary*

A review based on a PubMed search, with articles chosen by relevance, describes how optical coherence tomography has been applied to multiple sclerosis. According to its authors, thinning of the retinal nerve fibre and ganglion cell layers is associated with visual function, disability scores, and brain imaging measures, although disability correlations were not found in every study. The cause of thinning in eyes without prior optic neuritis remains disputed. Some studies suggest baseline nerve fibre thickness may help predict later disability worsening, and early thinning after acute optic neuritis may help predict visual recovery. Angiography applications rest on few studies, one of which discarded a substantial share of scans for poor quality, and clinical significance is unclear.

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