Optical coherence tomography angiography

AI Generated Summary*

A review of optical coherence tomography angiography, tracing its origins in Doppler OCT and explaining how motion contrast arises from comparing repeated B-scans. Topics include interscan time (4 to 5 ms in commercial devices, 1.5 ms or less in research prototypes) governing flow sensitivity and saturation, threshold masking and attenuation artifacts, en face projection versus cross-sectional and volume-rendered display, and deeper choroidal penetration at 1050 nm than 840 nm. Applications in retinal vascular occlusion, diabetic retinopathy, uveitis, inherited disease, macular degeneration and optic nerve disorders are surveyed. The central argument is that accurate interpretation requires understanding acquisition, processing and display, plus checking co-registered structural OCT, since missing signal does not prove absent flow.

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