Application of optical coherence tomography in multiple sclerosis: consensus recommendations of the Austrian network (AN-OCT-MS)

Published

2025

Audience

Therapeutic Area

Content Type

Peer-Reviewed Research

AI Generated Summary*

An Austrian expert network, using a modified nominal group technique with a predefined 80% agreement level, issued consensus recommendations on optical coherence tomography in multiple sclerosis. The panel agreed on four indications: supporting optic nerve involvement for dissemination in space, prognostic stratification of disability risk, quantifying damage at least three months after optic neuritis, and longitudinal monitoring. For monitoring, it gave no general recommendation, noting that experienced centers may use it within the clinical context. Standards for referral, device choice, scan protocol, quality control and reporting were also set. The authors state that the guidance rests on expert opinion rather than graded evidence, may not generalize beyond Austria, and leaves open whether imaging results should guide treatment.

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At a glance

Authors
Gabriel Bsteh; Luisa Velez Escola; Harald Hegen; Ewald Lindner; Michael Khalil; Sophie Schneider; Gerhard Traxler; Erich Raithel; Christian Bsteh; Christoph Mitsch; Thomas Berger; Berthold Pemp; Austrian Network for Optical Coherence in Multiple Sclerosis (AN-OCT-MS)
Publication
Journal of Neurology
Keywords
Optical Coherence Tomography; Multiple Sclerosis; Retinal Nerve Fiber Layer; Ganglion Cell Layer; Optic Neuritis; Neurodegeneration; Biomarker; Consensus
Year
2025
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