Agreement and Precision of Wide and Cube Scan Measurements between Swept-source and Spectral-domain OCT in Normal and Glaucoma Eyes

Published

2023

Audience

Therapeutic Area

Content Type

AI Generated Summary*

Fifty eyes (25 normal, 25 with glaucoma, mean deviation -5.30 dB) were imaged by three operators, each paired with one swept-source and one spectral-domain OCT. Three scans per configuration covered Wide (12 by 9 mm), macular cube and optic disc cube protocols, with circumpapillary RNFL, GCL+ and GCL++ thickness assessed for precision and between-device agreement. Precision was high and comparable for Wide and cube scans, most limits under 5 µm for macular and 10 µm for optic disc parameters. Wide scan differences between devices stayed at or below 3 µm (cpRNFL), 2 µm (GCL+) and 1 µm (GCL++), smaller than device axial resolution, though confidence intervals hinted at a small systematic GCL+ offset in glaucoma eyes; all participants were Caucasian.

*This summary was generated by AI and is published unedited. Oku does not alter these summaries. It may contain errors or omissions and is provided for general informational purposes only. Oku does not guarantee its accuracy, completeness, or reliability. For authoritative information, please refer to the original, peer-reviewed article.

At a glance

Authors
Huiyuan Hou; Nevin W. El-Nimri; Mary K. Durbin; Juan D. Arias; Sasan Moghimi; Robert N. Weinreb
Publication
Scientific Reports
Keywords
Glaucoma, Optic Disk, Retina, Kidney Tubules
Year
2023
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